SINGLE CELL LINEAGE TRACING REVEALS CLONAL DYNAMICS OF ANTI-EGFR THERAPY RESISTANCE IN TRIPLE NEGATIVE BREAST CANCER

Single cell lineage tracing reveals clonal dynamics of anti-EGFR therapy resistance in triple negative breast cancer

Abstract Background Most primary Triple Negative Breast Cancers (TNBCs) show amplification of the Epidermal Growth Factor Receptor (EGFR) gene, leading to increased protein Resveratrol expression.However, unlike other EGFR-driven cancers, targeting this receptor in TNBC yields inconsistent therapeutic responses.Methods To elucidate the underlying m

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DESIGN AND SIMULATION OF ASK 31 CHANNEL FREQUENCY HOPPING SPREAD SPECTRUM (FH/SS) TRANSCIEVER SYSTEM USING CONTIGUOUS BAND PASS FILTER BANKS

This paper propose a design and simulation of Amplitude Shift Keying (ASK ) 31 channel frequency hopping spread spectrum (FH/SS) transceiver system.The proposed design is implemented using Matlab/Simulink package.There are many available synchronization techniques that can be used in frequency hopping spread spectrum (FH/SS) transceiver system most

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Monoclonal antibodies and Fc fragments for treating solid tumors

Andrea M Eisenbeis, Stefan J GrauDepartment of Nail Files Neurosurgery, University Hospital of Cologne, Cologne, GermanyAbstract: Advances in biotechnology, better understanding of pathophysiological processes, as well as the identification of an increasing number of molecular markers have facilitated the use of monoclonal antibodies and Fc fragmen

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